Abstract:
Aza-Diels–Alder reaction between 3-(2-pyridyl)-1,2,4-triazines and 1-morpholinocyclohexene followed by aromatization of the cyclohexene moiety affords 1-(2-pyridyl)isoquinolines. Crystal structures of two tetrahydroisoquinolines were confirmed by X-ray diffraction analysis.
Citation:
D. S. Kopchuk, I. S. Kovalev, A. F. Khasanov, G. V. Zyryanov, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin, “A rational protocol for the synthesis of 1-(2-pyridyl)isoquinolines”, Mendeleev Commun., 23:3 (2013), 142–144
Linking options:
https://www.mathnet.ru/eng/mendc2641
https://www.mathnet.ru/eng/mendc/v23/i3/p142
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