Abstract:
Reaction between N,N-dimethylcarbamoylsilane and N,N-dimethyl-a-keto carboxamides affords 2-hydroxy-N,N,N’,N’-tetramethyl-2- R-malonamides in good yields.
Citation:
X. Chen, J. Chen, “Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides”, Mendeleev Commun., 23:2 (2013), 106–107
Linking options:
https://www.mathnet.ru/eng/mendc2631
https://www.mathnet.ru/eng/mendc/v23/i2/p106
This publication is cited in the following 10 articles:
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P. Zhang, Sh. Han, J. Chen, “The efficient synthesis of 3-hydroxyoxetane-3-carboxamides by the reaction of carbamoylsilanes with oxetan-3-one”, Mendeleev Commun., 29:3 (2019), 326–327
Jin-Yan Liang, Hui Wang, Yan-Li Yang, Shou-Jie Shen, Jian-Xin Chen, “Addition of carbamoylsilane to isatins: Highly efficient synthesis of 3-hydroxy-3-aminocarbonyl-2-oxindoles derivatives”, Tetrahedron Letters, 58:27 (2017), 2636
Xue-Ping Wen, Yu-Ling Han, Jian-Xin Chen, “Nickel-catalyzed aminocarbonylation of aryl halides using carbamoylsilane as an amide source”, RSC Adv., 7:71 (2017), 45107
Fei Ma, Hui Liu, Jianxin Chen, “Convenient method for the preparation of secondary α-ketoamides via aminocarbonylation of acid chlorides with carbamoylsilane”, Tetrahedron Letters, 57:47 (2016), 5246
Yanhong Liu, Pei Cao, Jianxin Chen, “Selective C H functionalization of electron-deficient aromatics by carbamoylsilanes: synthesis of aromatic carbinolamines or amides”, Tetrahedron Letters, 57:8 (2016), 937
Yu. Yao, W. Tong, J. Chen, “a-Hydroxy amides from carbamoylsilane and aldehydes”, Mendeleev Commun., 24:3 (2014), 176–177
Xiao Juan Chen, Jian Xin Chen, “ChemInform Abstract: Synthesis of 2‐Hydroxymalonamides from Carbamoylsilane and α‐Keto Carboxamides.”, ChemInform, 44:31 (2013)
Hui-Jun Zhang, Daniel L. Priebbenow, Carsten Bolm, “Acylsilanes: valuable organosilicon reagents in organic synthesis”, Chem. Soc. Rev., 42:21 (2013), 8540