Abstract:
(Z)-7-(3,5-Di-tert-butyl-6-oxocyclohexa-2,4-dien-1-ylidene)-1,3-dimethyl-3a,9a-diphenyl-1,3a,4,9a-tetrahydroimidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazine-2,8(3H,7H)-dione was obtained by aldol condensation of 3,5-di-tert-butyl-1,2-benzoquinone with 1,3-dimethyl-3a,9a-diphenyl-3,3a,9,9a-tetrahydroimidazo[4,5-e]thiazolo[3,2-b][1,2,4]triazine-2,7(1H,6H)-dione followed by intramolecular thiazole ring-opening/closing in the condensation primary adduct.
Document Type:
Article
Language: English
Citation:
A. N. Kravchenko, G. A. Gazieva, S. V. Vasilevskii, Yu. V. Nelyubina, “Cascade synthesis of the first imidazo[4,5-e]-thiazolo[2,3-c][1,2,4]triazine derivative”, Mendeleev Commun., 24:2 (2014), 119–121
Linking options:
https://www.mathnet.ru/eng/mendc2493
https://www.mathnet.ru/eng/mendc/v24/i2/p119
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Chita R. Sahoo, Sudhir K. Paidesetty, Rabindra N. Padhy, “Nornostocine congeners as potential anticancer drugs: An overview”, Drug Development Research, 80:7 (2019), 878
Galina A. Gazieva, Alexei N. Izmest'ev, Lada V. Anikina, Sergey A. Pukhov, Marina E. Meshchaneva, Dmitry V. Khakimov, Natalya G. Kolotyrkina, Angelina N. Kravchenko, “The influence of substituents on the reactivity and cytotoxicity of imidazothiazolotriazinones”, Mol Divers, 22:3 (2018), 585
Angelina N. Kravchenko, Sergei V. Vasilevskii, Galina A. Gazieva, Vladimir V. Baranov, Valery A. Barachevsky, Olga I. Kobeleva, Olga V. Venidiktova, Valentina A. Karnoukhova, “Transformations of S-substituted 5,7-dimethyl-4a,5a-diphenyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-2-ones under treatment of 1,2-benzoquinones and photochemical properties of reaction products”, Tetrahedron, 74:19 (2018), 2359
Galina A. Gazieva, Alexei N. Izmest'ev, Yulia V. Nelyubina, Natalya G. Kolotyrkina, Igor E. Zanin, Angelina N. Kravchenko, “Synthesis of imidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazine-2,8-diones via a rearrangement of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-2,7-diones in the reaction with isatins”, RSC Adv., 5:55 (2015), 43990
A. N. Kravchenko, S. V. Vasilevskii, G. A. Gazieva, Yu. V. Nelyubina, “Unexpected formation of 6-[benzofuran-3(2H)-ylidene]-3,3a,9,9a-tetra-hydroimidazo[4,5-e]thiazolo[3,2-b][1,2,4]triazine-2,7-dione derivative”, Mendeleev Commun., 25:6 (2015), 476–478
Angelina N. Kravchenko, Galina A. Gazieva, Sergei V. Vasilevskii, Yulia V. Nelyubina, “ChemInform Abstract: Cascade Synthesis of the First Imidazo[4,5‐e]thiazolo[2,3‐c][1,2,4]triazine Derivative (IV).”, ChemInform, 45:37 (2014)