Abstract:
The new multicomponent reaction of salicylaldehydes, 2-aminoprop-1-ene-1,1,3-tricarbonitrile and 3-phenylisoxazol-5(4H)-one gives substituted 2,4-diamino-5-(5-oxo-3-aryl-2,5-dihydroisoxazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitriles (50–74% yields), which are promising for biomedical applications.
Citation:
A. N. Vereshchagin, M. N. Elinson, Yu. E. Anisina, F. V. Ryzhkov, A. S. Goloveshkin, I. S. Bushmarinov, S. G. Zlotin, M. P. Egorov, “Pot, atom and step economic (PASE) synthesis of 5-isoxazolyl-5H-chromeno[2,3-b]pyridine scaffold”, Mendeleev Commun., 25:6 (2015), 424–426
Linking options:
https://www.mathnet.ru/eng/mendc2432
https://www.mathnet.ru/eng/mendc/v25/i6/p424
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