Abstract:
Computer docking studies suggest an explanation for better anticoagulant activity of fucosylated chondroitin sulfates as compared to non-fucosylated ones due to the formation of the ternary complex with thrombin and antithrombin III.
Document Type:
Article
Language: English
Citation:
A. G. Gerbst, N. E. Ustyuzhanina, N. E. Nifantiev, “Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates”, Mendeleev Commun., 25:6 (2015), 420–421
Linking options:
https://www.mathnet.ru/eng/mendc2430
https://www.mathnet.ru/eng/mendc/v25/i6/p420
This publication is cited in the following 7 articles:
Nadezhda E. Ustyuzhanina, Maria I. Bilan, Andrey S. Dmitrenok, Eugenia A. Tsvetkova, Sofya P. Nikogosova, Cao Thi Thuy Hang, Pham Duc Thinh, Dinh Thanh Trung, Tran Thi Thanh Van, Alexander S. Shashkov, Anatolii I. Usov, Nikolay E. Nifantiev, “Fucose-Rich Sulfated Polysaccharides from Two Vietnamese Sea Cucumbers Bohadschia argus and Holothuria (Theelothuria) spinifera: Structures and Anticoagulant Activity”, Marine Drugs, 20:6 (2022), 380
Alexey G. Gerbst, Vadim B. Krylov, Nikolay E. Nifantiev, “Conformational changes in common monosaccharides caused by per-O-sulfation”, Pure and Applied Chemistry, 91:7 (2019), 1223
A. N. Vereshchagin, “Classical and interdisciplinary approaches to the design of organic and hybrid molecular systems”, Russ Chem Bull, 66:10 (2017), 1765
Nadezhda E. Ustyuzhanina, Maria I. Bilan, Andrey S. Dmitrenok, Elizaveta Yu. Borodina, Valentin A. Stonik, Nikolay E. Nifantiev, Anatolii I. Usov, “A highly regular fucosylated chondroitin sulfate from the sea cucumber Massinium magnum : Structure and effects on coagulation”, Carbohydrate Polymers, 167 (2017), 20
Chuang Xiao, Wu Lian, Lutan Zhou, Na Gao, Li Xu, Jun Chen, Mingyi Wu, Wenlie Peng, Jinhua Zhao, “Interactions between depolymerized fucosylated glycosaminoglycan and coagulation proteases or inhibitors”, Thrombosis Research, 146 (2016), 59
Alexey G. Gerbst, Vadim B. Krylov, Dmitry A. Argunov, Arsenii S. Solovev, Andrey S. Dmitrenok, Alexander S. Shashkov, Nikolay E. Nifantiev, “Ring distortion in pyranosides caused by per-O-sulfation”, Carbohydrate Research, 436 (2016), 20
Nadezhda E Ustyuzhanina, Maria I Bilan, Andrey S Dmitrenok, Alexander S Shashkov, Mikhail I Kusaykin, Valentin A Stonik, Nikolay E Nifantiev, Anatolii I Usov, “Structure and biological activity of a fucosylated chondroitin sulfate from the sea cucumberCucumaria japonica”, Glycobiology, 26:5 (2016), 449
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