Abstract:
6-Amino-1,3-dimethyluracil reacts with two molecules of alkanals (butanal or pentanal) in formic acid to give 1,3,7,9-tetramethyl- 2,4,6,8-tetraoxopyrido[2,3-d][6,5-d’]dipyrimidine and the corresponding 3,4-dialkyl-substituted 6,8-dimethyl-5,7-dioxopyrido[2,3-d]- pyrimidines.
Document Type:
Article
Language: English
Citation:
Yu. A. Azev, O. S. Ermakova, A. M. Gibor, M. A. Ezhikova, M. I. Kodess, V. S. Berseneva, “Unusual reactions of 6-amino-1,3-dimethyluracil with some aliphatic aldehydes”, Mendeleev Commun., 25:4 (2015), 310–311
Linking options:
https://www.mathnet.ru/eng/mendc2392
https://www.mathnet.ru/eng/mendc/v25/i4/p310
This publication is cited in the following 7 articles:
Mohamed M. Hammouda, Khaled M. Elattar, Ayman Y. El-Khateeb, Sahar E. Hamed, Amany M. A. Osman, “Developments of pyridodipyrimidine heterocycles and their biological activities”, Mol Divers, 28:2 (2024), 927
Zeinab Hussain, Magdy A. Ibrahim, Nasser M. El-Gohary, Yassin A. Gabr, Hassan A. Allimony, Al-Shimaa Badran, “Utility of 6-Aminouracils for Building Substituted and Heteroannulated Pyrimidines: A Comprehensive Review”, HETEROCYCLES, 106:4 (2023), 594
Arvind Singh, Bhupinder Kaur, Aditi Sharma, Anu Priya, Manmeet Kaur, Mussarat Shamim, Bubun Banerjee, “One-pot multi-component synthesis of diverse bioactive heterocyclic scaffolds involving 6-aminouracil or its N-methyl derivatives as a versatile reagent”, Physical Sciences Reviews, 8:10 (2023), 3475
Zeinab Hussain, Magdy A. Ibrahim, Nasser M. El-Gohary, Al-Shimaa Badran, “Synthesis, characterization, DFT, QSAR, antimicrobial, and antitumor studies of some novel pyridopyrimidines”, Journal of Molecular Structure, 1269 (2022), 133870
Nibedita Baruah Dutta, Jugal Bori, Pinku Gogoi, Gakul Baishya, “Metal‐, Photocatalyst‐, Light‐ and Electrochemical‐Free C‐3 Trifluoromethylation of Quinoxalin‐2(1H)‐ones, Imidazo[1,2‐a]pyridines and 2H‐Indazoles”, ChemistrySelect, 6:7 (2021), 1471
Yurii A. Azev, Ol'ga S. Ermakova, Alexey M. Gibor, Marina A. Ezhikova, Mikhail I. Kodess, Vera S. Berseneva, “ChemInform Abstract: Unusual Reactions of 6‐Amino‐1,3‐dimethyluracil with Some Aliphatic Aldehydes.”, ChemInform, 47:1 (2016)
Yu. A. Azev, O. S. Ermakova, A. M. Gibor, V. A. Bakulev, M. A. Ezhikova, M. I. Kodess, “Synthesis of pyrido[2,3-d]pyrimidines from 6-amino-1,3-dimethyluracil and aldehydes”, Russ J Org Chem, 51:12 (2015), 1784
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