Abstract:
3-Bromomethyl-2,8-dioxaspiro[4.4]nonane-1,6-diones were efficiently prepared from 3-ethoxycarbonyltetrahydrofuran-2-ones. Subsequent conversion of the bromomethyl group into azidomethyl one followed by click reaction with alkynes afforded the multifunctional triazole-containing spiro dilactones in almost quantitative yields.
Citation:
T. V. Ghochikyan, V. M. Muzalevskiy, M. A. Samvelyan, A. S. Galstyan, V. G. Nenajdenko, “Efficient synthesis of triazole-containing spiro dilactones”, Mendeleev Commun., 26:1 (2016), 11–13
Linking options:
https://www.mathnet.ru/eng/mendc2092
https://www.mathnet.ru/eng/mendc/v26/i1/p11
This publication is cited in the following 6 articles:
Armen S. Galstyan, Sevak V. Grigoryan, Melanya A. Samvelyan, Vardges R. Frangyan, Tigran H. Yeganyan, Armen G. Ayvazyan, Tariel V. Ghochikyan, “On Features of Halocyclization of 4‐Allyl‐5‐substituted‐2,4‐dihydro‐3H‐1,2,4‐triazol‐3‐thiones and Synthesis of New Derivatives of 1,2,3‐Triazoles”, ChemistrySelect, 7:19 (2022)
Hamdi Rmedi, “Design and synthesis of fused cyclic sulfamides-oxazolidinones”, Tetrahedron, 75:10 (2019), 1337
E. V. Tret'yakova, E. V. Salimova, E. R. Shakurova, L. V. Parfenova, V. N. Odinokov, “One-pot synthesis of 1,2,3-triazole derivatives of maleopimaric and dihydroquinopimaric acids”, Russ J Org Chem, 53:11 (2017), 1701
T. V. Ghochikyan, M. A. Samvelyan, A. S. Galstyan, V. M. Muzalevskiy, V. G. Nenajdenko, “Copper catalyzed alkyne–azide cycloaddition with 3-propargyl- γ-butyrolactones”, Mendeleev Commun., 27:6 (2017), 562–564
Tariel V. Ghochikyan, Vasily M. Muzalevskiy, Melanya A. Samvelyan, Armen S. Galstyan, Valentine G. Nenajdenko, “ChemInform Abstract: Efficient Synthesis of Triazole‐Containing Spiro Dilactones.”, ChemInform, 47:24 (2016)
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