Abstract:
3-Bromomethyl-2,8-dioxaspiro[4.4]nonane-1,6-diones were efficiently prepared from 3-ethoxycarbonyltetrahydrofuran-2-ones. Subsequent conversion of the bromomethyl group into azidomethyl one followed by click reaction with alkynes afforded the multifunctional triazole-containing spiro dilactones in almost quantitative yields.
Citation:
T. V. Ghochikyan, V. M. Muzalevskiy, M. A. Samvelyan, A. S. Galstyan, V. G. Nenajdenko, “Efficient synthesis of triazole-containing spiro dilactones”, Mendeleev Commun., 26:1 (2016), 11–13
Linking options:
https://www.mathnet.ru/eng/mendc2092
https://www.mathnet.ru/eng/mendc/v26/i1/p11
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