Abstract:
A highly efficient ‘green’ solvent-free monoarylation of primary anilines with aryl bromides mediated by the expanded-ring N-heterocyclic carbene palladium complex (THP-Dipp)Pd(cinn)Cl [THP-Dipp is 1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene; cinn is cinnamyl] can be performed at low catalyst loadings (0.1 mol%) to provide excellent yields and remarkable selectivities for various substrates.
Document Type:
Article
Language: English
Citation:
G. A. Chesnokov, P. S. Gribanov, M. A. Topchiy, L. I. Minaeva, A. F. Asachenko, M. S. Nechaev, E. V. Bermesheva, M. V. Bermeshev, “Solvent-free Buchwald–Hartwig amination with low palladium loadings”, Mendeleev Commun., 27:6 (2017), 618–620
Linking options:
https://www.mathnet.ru/eng/mendc2079
https://www.mathnet.ru/eng/mendc/v27/i6/p618
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