Abstract:
Copper catalyzed [2 + 3] cycloaddition of 3-propargyl- γ-butyrolactones with azides affords the corresponding 1,2,3-triazoles connected with lactone moiety in high yields. In the presence of air and copper(i) halides, the starting propargylated lactones are prone to dimerize to form bis-lactone diynes.
Citation:
T. V. Ghochikyan, M. A. Samvelyan, A. S. Galstyan, V. M. Muzalevskiy, V. G. Nenajdenko, “Copper catalyzed alkyne–azide cycloaddition with 3-propargyl- γ-butyrolactones”, Mendeleev Commun., 27:6 (2017), 562–564
Linking options:
https://www.mathnet.ru/eng/mendc2059
https://www.mathnet.ru/eng/mendc/v27/i6/p562
This publication is cited in the following 1 articles:
Maxim A. Topchiy, Alexandra A. Ageshina, Gleb A. Chesnokov, Grigorii K. Sterligov, Sergey A. Rzhevskiy, Pavel S. Gribanov, Sergey N. Osipov, Mikhail S. Nechaev, Andrey F. Asachenko, “Alkynyl‐ or Azido‐Functionalized 1,2,3‐Triazoles: Selective MonoCuAAC Promoted by Physical Factors”, ChemistrySelect, 4:25 (2019), 7470