Abstract:
6-O-Acylated phaeosphaeride A and phaeosphaeride B in reaction with secondary cyclic amines undergo stereospecific replacement of acyloxy group by pharmacophoric amino moiety. In case of chloroacetoxy derivative, chlorine displacement by such amines proceeds in the presence of triethylamine.
Citation:
V. V. Abzianidze, K. P. Efimova, E. V. Poluektova, Yu. G. Trishin, V. A. Kuznetsov, “Synthesis of natural phaeosphaeride A and semi-natural phaeosphaeride B derivatives”, Mendeleev Commun., 27:5 (2017), 490–492
Linking options:
https://www.mathnet.ru/eng/mendc2037
https://www.mathnet.ru/eng/mendc/v27/i5/p490
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