Abstract:
The reaction of 2-alkyl-substituted 5-, 6- and 7-membered cyclic imines with a-bromo ketones in the presence of Hünig's base affords 2,3-dihydro-1H-pyrrolizines, 5,6,7,8-tetrahydroindolizines and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]azepines, respectively.
Document Type:
Article
Language: English
Citation:
O. I. Shmatova, V. G. Nenajdenko, “Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones”, Mendeleev Commun., 28:3 (2018), 270–271
Linking options:
https://www.mathnet.ru/eng/mendc1734
https://www.mathnet.ru/eng/mendc/v28/i3/p270
This publication is cited in the following 2 articles:
O. V. Zvereva, T. S. Rizbaeva, M. A. Shmelev, E. N. Zorina-Tikhonova, J. K. Voronina, I. L. Eremenko, “Experimental and Theoretical Study of the Structure of 3-Arylidene-1-Pyrrolinium Salts”, J Struct Chem, 65:7 (2024), 1439
A.S. Gazizov, A.V. Smolobochkin, A.R. Burilov, M.A. Pudovik, “3-Ylidene-1-pyrrolines: Synthesis, reactions and perspectives”, Tetrahedron Letters, 61:39 (2020), 152371
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