Abstract:
New conjugates of cholesterol and cobalt bis(dicarbollide) were synthesized using ‘click’ cycloaddition of 3b-(2-azidoethyl) cholest-5-ene and acetylene-equipped cobalt bis(dicarbollides). The synthesized boronated cholesterols can be of interest for liposomal drug delivery for boron neutron capture therapy of cancer.
Citation:
A. A. Druzina, A. V. Shmalko, E. P. Andreichuk, O. B. Zhidkova, I. D. Kosenko, A. A. Semioshkin, I. B. Sivaev, S. Mandal, Zh. Shen, V. I. Bregadze, “‘Click’ synthesis of cobalt bis(dicarbollide)–cholesterol conjugates”, Mendeleev Commun., 29:6 (2019), 628–630
Linking options:
https://www.mathnet.ru/eng/mendc1610
https://www.mathnet.ru/eng/mendc/v29/i6/p628
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