Abstract:
Reaction between arylidenemalononitriles and acetoacetanilide in the presence of piperazine hydrate in methanol at room temperature affords new tricyclic pyrano[3,2-c]pyridine derivatives of (rac-1S*,2R*,3R*,7R*,8R*,11R*)-2,11-diaryl-4,10-diimino-8-methyl-5-phenyl-6-oxo-9-oxa-5-azatricyclo-[5.3.1.03,8]undecane-1,3-dicarbonitrile family in yields of 55–84%. The molecular structures of the products were confirmed by X-ray crystallography and NMR spectroscopy.
Citation:
I. G. Mamedov, V. N. Khrustalev, P. V. Dorovatovskii, F. N. Naghiev, A. M. Maharramov, “Efficient synthesis of new tricyclic pyrano[3,2-c]pyridine derivatives”, Mendeleev Commun., 29:2 (2019), 232–233
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https://www.mathnet.ru/eng/mendc1482
https://www.mathnet.ru/eng/mendc/v29/i2/p232
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