S. V. Blagodarov, G. A. Zheltukhina, A. S. Urban, E. E. Shishkina, V. E. Nebolsin, “Synthesis of cyclic norspermidine derivative of protohemin IX”, Mendeleev Commun., 29:2 (2019), 209

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Mendeleev Communications, 2019, Volume 29, Issue 2, Pages 209–211
DOI: https://doi.org/10.1016/j.mencom.2019.03.032 (Mi mendc1474)

Communications

Synthesis of cyclic norspermidine derivative of protohemin IX

S. V. Blagodarov^a, G. A. Zheltukhina^a, A. S. Urban^bc, E. E. Shishkina^a, V. E. Nebolsin^d

^a M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
^b M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^c Moscow Institute of Physics and Technology (National Research University), Dolgoprudny, Moscow Region, Russian Federation
^d Pharminterprices Ltd., Moscow, Russian Federation

Full-text PDF (312 kB)

DOI: https://doi.org/10.1016/j.mencom.2019.03.032

Graphic abstract: Synthesis of cyclic norspermidine derivative of protohemin IX

Abstract: A simple synthesis of cyclic norspermidine derivative of protohemin IX without the use of selective protecting groups has been developed. The obtained water-soluble protohemin IX derivative has antibacterial activity and is non-toxic at a concentration of 250μgml⁻¹.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(198.2 Kb)

Citation: S. V. Blagodarov, G. A. Zheltukhina, A. S. Urban, E. E. Shishkina, V. E. Nebolsin, “Synthesis of cyclic norspermidine derivative of protohemin IX”, Mendeleev Commun., 29:2 (2019), 209–211

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