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Mendeleev Communications, 2020, Volume 30, Issue 6, Pages 747–749
DOI: https://doi.org/10.1016/j.mencom.2020.11.019
(Mi mendc1312)
 

This article is cited in 4 scientific papers (total in 4 papers)

Communications

Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging

M. S. Oshchepkova, A. S. Semyonkina, A. O. Menkova, P. A. Melnikovb, M. P. Valikhovb, I. N. Solovievaa, S. V. Tkachenkoa, J. A. Malinowskayab

a D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
b V.P. Serbsky National Medical Research Centre of Psychiatry and Narcology, Moscow, Russian Federation
Abstract: Two strategies for the synthesis of the new fluorescent markers based on 1,8-naphthalimide under classical conditions (in a flask) and in a microflow reactor are compared and contrasted. The microflow method provides higher purity of products, better productivity and production time. The resulting markers were used to obtain fluorescently labeled polylactide-based nanoparticles that can be used to study the distribution of polylactide nanoparticles as drug delivery vehicles within tissues and living organisms.
Keywords: microfluidic synthesis, fluorescent markers, polylactide, 1,8-naphthalimide, bioimaging.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.9 Mb)


Citation: M. S. Oshchepkov, A. S. Semyonkin, A. O. Menkov, P. A. Melnikov, M. P. Valikhov, I. N. Solovieva, S. V. Tkachenko, J. A. Malinowskaya, “Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging”, Mendeleev Commun., 30:6 (2020), 747–749
Linking options:
  • https://www.mathnet.ru/eng/mendc1312
  • https://www.mathnet.ru/eng/mendc/v30/i6/p747
  • This publication is cited in the following 4 articles:
    1. Konstantin A. Kochetkov, Maxim S. Oshchepkov, Pavel A. Pavlov, Michail M. Il'in, Inna N. Soloveva, Alexander S. Oshchepkov, “Green chemistry approach for stereoselective aldol condensation catalyzed by amino acids under microflow conditions”, Chemical Engineering Research and Design, 201 (2024), 169  crossref
    2. Maxim Oshchepkov, Sergey Tkachenko, Konstantin Popov, Aleksey Semyonkin, Danil Yuriev, Inna Solovieva, Pavel Melnikov, Julia A. Malinovskaya, Alexander Oshchepkov, “Continuous-flow synthesis of the naphthalimide derivatives for medical and engineering applications”, Dyes and Pigments, 231 (2024), 112386  crossref
    3. A.A. Lubin, R.V. Yakushin, M.S. Oshchepkov, Yu.V. Ulyanova, D.O. Botev, A.V. Chistolinov, N.Ya. Podhaluzina, I.N. Solovieva, V.S. Boldyrev, “Acenaphthene Nitro Derivatives Plasma-Chemical Synthesis in the High-Frequency Currents Field at Reduced Pressure”, HoBMSTU.SNS, 2023, no. 4 (109), 123  crossref
    4. M. A. Merkulova, N. S. Osipova, O. O. Maksimenko, M. G. Gordienko, S. E. Gelperina, “Easy size control of polymer nanoparticles obtained by emulsification–evaporation technique in a microfluidic reactor”, Mendeleev Commun., 31:6 (2021), 899–901  mathnet  crossref
    Citing articles in Google Scholar: Russian citations, English citations
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