Abstract:
Hybrids composed of 3-pentylnorbornadiene-2-carboxylic acid or its quadricyclane isomer molecules linked to methano-C60 fullerene via triethylene glycol spacer were synthesized by the Bingel–Hirsch reaction. The quadricyclane derivative possesses markedly higher apoptosis-inducing activity against the Jurkat tumor cells than the norbornadiene one.
Citation:
U. M. Dzhemilev, A. R. Akhmetov, V. A. D'yakonov, L. U. Dzhemileva, M. M. Yunusbaeva, A. R. Tuktarov, “Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties”, Mendeleev Commun., 30:2 (2020), 150–152
Linking options:
https://www.mathnet.ru/eng/mendc1130
https://www.mathnet.ru/eng/mendc/v30/i2/p150
This publication is cited in the following 3 articles:
Arslan R. Akhmetov, Zarema R. Sadretdinova, Arthur R. Tulyabaev, Leonard M. Khalilov, ECSOC 2023, 2023, 67
Arslan Akhmetov, Zarema Sadretdinova, Lilya U. Dzhemileva, Airat Tuktarov, Usein Dzhemilev, The 25th International Electronic Conference on Synthetic Organic Chemistry, 2021, 95
V. S. Romanova, N. Yu. Shepeta, Z. S. Klemenkova, K. A. Kochetkov, “Catalytically active hybrid complex of fullerene C60 and vitamine B12”, Mendeleev Commun., 31:6 (2021), 844–846