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Mendeleev Communications, 2021, Volume 31, Issue 5, Pages 615–617
DOI: https://doi.org/10.1016/j.mencom.2021.09.008
(Mi mendc1000)
 

This article is cited in 10 scientific papers (total in 10 papers)

Communications

Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents

I. A. Doroshenkoa, K. G. Aminullaa, V. N. Azevb, T. M. Kulinichc, V. A. Vasilichina, A. A. Shtilad, T. A. Podruginaa

a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
b Branch of M.M. Shemyakin–Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation
c Russian Scientific Center of Roentgenoradiology, Moscow, Russian Federation
d N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation
Abstract: New β-alanine modified tricarbocyanines containing various substituents at quaternized nitrogen atoms were obtained. The peptide synthesis method has been utilized for further conjugation thus giving promising tricarbocyanines containing two sulfonate groups and total negative charge of the fluorophore.
Keywords: fluorophores, conjugates, β-alanine, cell-penetrating peptides, tricarbocyanine dyes, Fluorescent markers.
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (970.0 Kb)


Citation: I. A. Doroshenko, K. G. Aminulla, V. N. Azev, T. M. Kulinich, V. A. Vasilichin, A. A. Shtil, T. A. Podrugina, “Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents”, Mendeleev Commun., 31:5 (2021), 615–617
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  • https://www.mathnet.ru/eng/mendc/v31/i5/p615
  • This publication is cited in the following 10 articles:
    1. A. A. Uspenskaia, I. A. Doroshenko, K. A. Popovicheva, N. V. Shmychkov, I. I. Levina, M. K. Beklemishev, V. N. Tashlitsky, T. A. Podrugina, A. E. Machulkin, E. K. Beloglazkina, Mendeleev Commun., 35:2 (2025), 172–175  mathnet  crossref
    2. Anna V. Shik, Irina A. Stepanova, Marina V. Koksharova, Irina A. Doroshenko, Tatyana A. Podrugina, Ulyana A. Bliznyuk, Polina Yu. Borshchegovskaya, Alexander P. Chernyaev, Irina A. Ananieva, Igor A. Rodin, Mikhail K. Beklemishev, “Estimation of irradiation doses in chicken samples using a reaction-based fingerprinting method”, Food Chemistry, 2025, 144073  crossref
    3. Anna V. Shik, Pavel V. Sobolev, Yana V. Zubritskaya, Maksim O. Baytler, Irina A. Stepanova, Alexander P. Chernyaev, Polina Yu. Borschegovskaya, Sergey A. Zolotov, Irina A. Doroshenko, Tatyana A. Podrugina, Ulyana A. Bliznyuk, Igor A. Rodin, Mikhail K. Beklemishev, “Rapid testing of irradiation dose in beef and potatoes by reaction-based optical sensing technique”, Journal of Food Composition and Analysis, 127 (2024), 105946  crossref
    4. E. V. Skorobogatov, Yu. V. Timchenko, I. A. Doroshenko, T. A. Podrugina, I. A. Rodin, M. K. Beklemishev, “Determination of Isoniazid by a Photometric Method due to Covalent Binding with a Carbocyanine Dye”, J Anal Chem, 79:4 (2024), 417  crossref
    5. A. A. Luenkova, I. A. Doroshenko, T. A. Podrugina, M. K. Beklemishev, “Fluorescing Ternary Aggregates Containing a Carbocyanine Dye and Laurate Ion for Imaging-Guided Delivery of Hydrophilic Drugs to Tissues”, Nanotechnol Russia, 19:1 (2024), 17  crossref
    6. Evgenii V. Skorobogatov, Anna V. Shik, Pavel V. Sobolev, Irina A. Stepanova, Vladislav S. Orekhov, Alexander O. Ustyuzhanin, Marina V. Koksharova, Yury A. Ikhalaynen, Yury V. Timchenko, Igor A. Rodin, Mikhail K. Beklemishev, “Monitoring Different Water Types for Engine Oil–Water-Soluble Fraction and Iron(2+) Using a Reaction-Based Optical Sensing Strategy: A Proof-of-Concept Study”, Ind. Eng. Chem. Res., 63:28 (2024), 12336  crossref
    7. Anna V. Shik, Evgenii V. Skorobogatov, Ramil M. Akhmetov, Irina A. Doroshenko, Tatyana A. Podrugina, Gleb K. Sugakov, Mikhail K. Beklemishev, “A Reaction-Based Approach to Colorimetric Detection of Organic Analytes in Water Using a Chlorine-Containing Carbocyanine Dye and Hypochlorite”, Chemosensors, 12:11 (2024), 224  crossref
    8. E. V. Skorobogatov, Yu. V. Timchenko, I. A. Doroshenko, T. A. Podrugina, I. A. Rodin, M. K. Beklemishev, “Determination of isoniazid by photometric method through covalent binding with carbocyanine dye”, Zhurnal Analiticheskoi Khimii, 79:5 (2024), 470  crossref
    9. Anna V. Shik, Evgenii V. Skorobogatov, Ulyana A. Bliznyuk, Alexander P. Chernyaev, Valentina M. Avdyukhina, Polina Yu. Borschegovskaya, Sergey A. Zolotov, Maksim O. Baytler, Irina A. Doroshenko, Tatyana A. Podrugina, Mikhail K. Beklemishev, “Estimation of doses absorbed by potato tubers under electron beam or X-ray irradiation using an optical fingerprinting strategy”, Food Chemistry, 414 (2023), 135668  crossref
    10. A. S. Efimova, M. A. Ustimova, M. A. Maksimova, A. Yu. Frolova, V. I. Martynov, S. M. Deyev, A. A. Pakhomov, Yu. V. Fedorov, O. A. Fedorova, “Synthesis and optical characteristics of 4-styrylpyridinium dyes and their conjugates with antibody”, Mendeleev Commun., 33:3 (2023), 384–386  mathnet  crossref
    Citing articles in Google Scholar: Russian citations, English citations
    Related articles in Google Scholar: Russian articles, English articles
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