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Commentary on the Work of Jimak S.S. et al. "Mathematical Modeling of Open States in Double Stranded DNA Molecule Depending on $^2$H/$^1$H Ratio"
A. S. Shigaev Institute of Mathematical Biology RAS, M.V. Keldysh Institute of Applied Mathematics of RAS, Pushchino, Russia
Abstract:
The article is analyzed Jimak S.S. et al. "Mathematical modeling of open state accounting as a function of $^2$H/$^1$H ratio in a double-stranded DNA molecule", appeared in “Mathematical Biology and Bioinformatics”. The values of H-bond energies used in the simulation as a parameter are estimated. A new mechanism for the effect of DNA deuteration on biological function of DNA described by authors is proposed.
Key words:
open state of DNA, DNA deuteration, angular mechanical model.
Received 22.12.2019, Published 16.01.2020
Citation:
A. S. Shigaev, “Commentary on the Work of Jimak S.S. et al. "Mathematical Modeling of Open States in Double Stranded DNA Molecule Depending on $^2$H/$^1$H Ratio"”, Mat. Biolog. Bioinform., 15:1 (2020), 1–3
Linking options:
https://www.mathnet.ru/eng/mbb418 https://www.mathnet.ru/eng/mbb/v15/i1/p1
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