Abstract:
Method recognizing the flavivirus species, including a subtype recognition, that based on the genome sequence analysis, is proposed. This method takes into consideration frequency characteristics of amino acid codons in the coding sequences of full-length polyprotein of flavivirus genomes. High reliability of the method is proved in recognizing flavivirus genomes from 15 groups of different species and sub-types, that are sufficiently represented in the GenBank database. Ten various species of the flaviviruses, four sub-types of Dengue virus and Kunjin virus, that is suggested to be a sub-type of West Nile virus, are considered in the work.
Key words:
flavivirus genome, latent profile triplet periodicity, frequencies of amino acid codons, flavivirus species recognition.
Received 28.08.2019, 13.11.2019, Published 19.11.2019
Document Type:
Article
Language: Russian
Citation:
M. B. Chaley, Zh. S. Tyulko, V. A. Kutyrkin, “Flavivirus species recognition based on the polyprotein coding sequences”, Mat. Biolog. Bioinform., 14:2 (2019), 533–542