Abstract:
Method recognizing the flavivirus species, including a subtype recognition, that based on the genome sequence analysis, is proposed. This method takes into consideration frequency characteristics of amino acid codons in the coding sequences of full-length polyprotein of flavivirus genomes. High reliability of the method is proved in recognizing flavivirus genomes from 15 groups of different species and sub-types, that are sufficiently represented in the GenBank database. Ten various species of the flaviviruses, four sub-types of Dengue virus and Kunjin virus, that is suggested to be a sub-type of West Nile virus, are considered in the work.
Key words:
flavivirus genome, latent profile triplet periodicity, frequencies of amino acid codons, flavivirus species recognition.
Received 28.08.2019, 13.11.2019, Published 19.11.2019
Document Type:
Article
Language: Russian
Citation:
M. B. Chaley, Zh. S. Tyulko, V. A. Kutyrkin, “Flavivirus species recognition based on the polyprotein coding sequences”, Mat. Biolog. Bioinform., 14:2 (2019), 533–542
\Bibitem{ChaTyuKut19}
\by M.~B.~Chaley, Zh.~S.~Tyulko, V.~A.~Kutyrkin
\paper Flavivirus species recognition based on the polyprotein coding sequences
\jour Mat. Biolog. Bioinform.
\yr 2019
\vol 14
\issue 2
\pages 533--542
\mathnet{http://mi.mathnet.ru/mbb401}
\crossref{https://doi.org/10.17537/2019.14.533}
Linking options:
https://www.mathnet.ru/eng/mbb401
https://www.mathnet.ru/eng/mbb/v14/i2/p533
This publication is cited in the following 6 articles:
M.B. Chaley, V.A. Kutyrkin, “Typological Approaches to Recognizing Genus and Subgenus of Coronaviruses by Structural and Non-Structural Genes”, Math.Biol.Bioinf., 19:2 (2025), 593
M. B. Chalei, V. A. Kutyrkin, “Raspoznavanie roda koronavirusa na osnove prototipnykh shtammov”, Matem. biologiya i bioinform., 17:1 (2022), 10–27
M.B. Chaley, V.A. Kutyrkin, Proceedings of the International Conference “Mathematical Biology and Bioinformatics”, 9, Proceedings of the International Conference “Mathematical Biology and Bioinformatics”, 2022
Maria Chaley, Vladimir Kutyrkin, 2022 Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine (CSGB), 2022, 170
M. B. Chalei, Zh. S. Tyulko, V. A. Kutyrkin, “Issledovanie struktury kodirovaniya ORF1ab, S, M i N genov koronavirusov”, Matem. biologiya i bioinform., 15:2 (2020), 441–454
M.B. Chaley, Zh.S. Tyulko, V.A. Kutyrkin, Proceedings of the International Conference “Mathematical Biology and Bioinformatics”, 8, Proceedings of the International Conference “Mathematical Biology and Bioinformatics”, 2020