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This article is cited in 3 scientific papers (total in 3 papers)
Translations of Published Articles
Phenotypic variability of bacterial cell cycle: mathematical model
V. A. Likhoshvaiab, T. M. Khlebodarovab a Novosibirsk State University, Novosibirsk, 630090 Russia
b Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences,
Novosibirsk, 630090 Russia
Abstract:
Modeling results demonstrating mechanisms of different cell phenotypes appearance in a genetically homogenous population using the bacterial cell cycle model are presented. It was demonstrated that phenotypic variability represents an internal, immanent property of bacteria. The basis of this phenomenon is universal non-linear properties of the conjugated transcription-translation system that controls all cellular processes. Phenotypic variability occurs in a simple, deterministic, self-reproducing system under the uniform transmission of the structural components to the daughter cells during division and in the absence of any special control mechanisms of molecular-genetic processes and enzymatic reactions.
Key words:
bacteria, cell cycle, modelling, phenotypic variability.
Received 03.07.2017, Published 15.09.2017
Citation:
V. A. Likhoshvai, T. M. Khlebodarova, “Phenotypic variability of bacterial cell cycle: mathematical model”, Mat. Biolog. Bioinform., 12, Suppl. (2017), t23–t44
Linking options:
https://www.mathnet.ru/eng/mbb316 https://www.mathnet.ru/eng/mbb/v12/i3/p23
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Abstract page: | 196 | Full-text PDF : | 55 | References: | 38 |
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