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Matematicheskaya Biologiya i Bioinformatika, 2017, Volume 12, Issue 2, Pages 343–353
DOI: https://doi.org/10.17537/2017.12.343
(Mi mbb298)
 

This article is cited in 1 scientific paper (total in 1 paper)

Bioinformatics

Structural-statistical properties of the flavivirus genomes

Zh. S. Tyulkoa, V. A. Kutyrkinb, M. B. Chaleyc

a Omsk State Medical University of Ministry of Healthcare of the Russian Federation, Omsk, 644099, Russia
b Moscow State Technical University n.a. N.E. Bauman, Moscow, 107005, Russia
c Institute of Mathematical Problems of Biology RAS – the Branch of Keldysh Institute of Applied Mathematics of Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
Full-text PDF (948 kB) Citations (1)
References:
Abstract: Essential structural-statistical properties of coding regions in the genomes of flaviviruses are investigated on base of the Spectral-statistical approach. Both full-length polyprotein coding sequences and their separated structural segments are analyzed. On the whole, structural-statistical properties of the flavivirus genome sequences are shown to be similar to the properties of 3-regularity and latent triplet profile periodicity revealed earlier in the coding regions of prokaryotic and eukaryotic genomes. However, two-level organization of coding is not occurred in discrete segments coding for structural proteins in the flavivirus genomes and property of sequence homogeneity is manifested in significant part of such the segments. These coding sequence particularities are explained by simple structure and high mutation rate of the flavivirus genomes.
Key words: flavivirus genome, prokaryotic genome, eukaryotic genome, spectral-statistical approach, latent profile periodicity, property of 3-regularity.
Funding agency Grant number
Russian Foundation for Basic Research 15-07-05783_а
Received 08.09.2017, Published 12.10.2017
Document Type: Article
UDC: 577.2:519.23
Language: Russian
Citation: Zh. S. Tyulko, V. A. Kutyrkin, M. B. Chaley, “Structural-statistical properties of the flavivirus genomes”, Mat. Biolog. Bioinform., 12:2 (2017), 343–353
Citation in format AMSBIB
\Bibitem{TyuKutCha17}
\by Zh.~S.~Tyulko, V.~A.~Kutyrkin, M.~B.~Chaley
\paper Structural-statistical properties of the flavivirus genomes
\jour Mat. Biolog. Bioinform.
\yr 2017
\vol 12
\issue 2
\pages 343--353
\mathnet{http://mi.mathnet.ru/mbb298}
\crossref{https://doi.org/10.17537/2017.12.343}
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  • https://www.mathnet.ru/eng/mbb/v12/i2/p343
  • This publication is cited in the following 1 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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    Full-text PDF :42
    References:27
     
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