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This article is cited in 2 scientific papers (total in 2 papers)
Mathematical Modeling
Mathematical model of the humoral immune response: focusing on Th17 autoimmunity
S. R. Kuznetsov Saint Petersburg State University
Abstract:
This work is devoted to development of mathematical model, describing processes of Th and B lymphocyte proliferation and differentiation, as well as IFN-$\gamma$, IL-2, IL-4 and IL-21 cytokine secretion. New approaches are suggested, allowing more accurate modelling. Special attention paid to Th17 lymphocyte impact to effect of plasma cells and IgM and IgG antibody level increasing.
Key words:
systems immunology, lymphocyte, cytokine network, IgM, IgG, IL-17.
Received 04.09.2015, Published 23.11.2015
Citation:
S. R. Kuznetsov, “Mathematical model of the humoral immune response: focusing on Th17 autoimmunity”, Mat. Biolog. Bioinform., 10:2 (2015), 455–472
Linking options:
https://www.mathnet.ru/eng/mbb238 https://www.mathnet.ru/eng/mbb/v10/i2/p455
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