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Matematicheskaya Biologiya i Bioinformatika, 2007, Volume 2, Issue 1, Pages 20–35
(Mi mbb14)
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This article is cited in 6 scientific papers (total in 6 papers)
Proceedings of The International Conference "Mathematical Biology and Bioinformatics"
Joint use of different homogeneity testing criteria for latent periodicity revelation in biological sequences
M. B. Chaleya, N. N. Nazipovaa, V. A. Kutyrkinb a Institute of Mathematical Problems of Biology, Russian Academy of Sciences
b N. E. Bauman Moscow State Technical University
Abstract:
A model of additional statistical experiments has been used in this work to reveal latent periodicity in biological sequences. This model which generalizes a notion of fuzzy tandem repeats (FTRs) has allowed us to propose original statistical methods for estimation of periodicity pattern in the approximate tandem repeats (ATRs). It has been shown that if indels' percentage in approximate tandem repeats is high, then for a number of cases the alignment of copies which is based on approximation of repeat’s pattern size according to this model appears to be more optimal, compared with alignment obtained by well know Tandem Repeats Finder method (TRF). Compared with existing analogs, the proposed methods have greater power. The main advantage of the proposed methods is in their applicability in practical conditions of unrepresentative sample.
Key words:
latent periodicity, test-period, profile matrix, spectrum of relative amplitudes.
Received 30.03.2007, Published 22.04.2007
Citation:
M. B. Chaley, N. N. Nazipova, V. A. Kutyrkin, “Joint use of different homogeneity testing criteria for latent periodicity revelation in biological sequences”, Mat. Biolog. Bioinform., 2:1 (2007), 20–35
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https://www.mathnet.ru/eng/mbb14 https://www.mathnet.ru/eng/mbb/v2/i1/p20
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Abstract page: | 346 | Full-text PDF : | 113 | References: | 61 | First page: | 1 |
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