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III International Conference Physics -- Life Sciences
Polymer materials for biomedicine
The effect of ammonium chloride on the structure of hydroxyapatite nanoparticles and the proliferative activity of mesenchymal stromal cells
I. P. Dobrovol'skayaab, K. V. Malafeeva, Yu. A. Nashchekinaac, I. A. Kasatkind, E. N. Popovab, V. E. Yudinab a Peter the Great St. Petersburg Polytechnic University
b Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg
c Institute of Cytology Russian Academy of Science, St. Petersburg
d Saint Petersburg State University
Abstract:
Synthetic hydroxyapatite nanoparticles that contain ammonium chloride crystals are obtained. The X-ray diffraction, thermogravimetric analysis, and BET methods show that ammonium chloride crystals are decomposed in argon in the temperature range of $T$ = 220–270$^\circ$C. The heat treatment at $T$ = 300$^\circ$C gives thermal stability to the nanoparticles. The presence of ammonium chloride in the culture medium has a substantial effect on the biocompatibility of nanoparticles. An increase in its content reduces the proliferative activity of mesenchymal stromal cells.
Received: 21.01.2020 Revised: 10.04.2020 Accepted: 10.04.2020
Citation:
I. P. Dobrovol'skaya, K. V. Malafeev, Yu. A. Nashchekina, I. A. Kasatkin, E. N. Popova, V. E. Yudin, “The effect of ammonium chloride on the structure of hydroxyapatite nanoparticles and the proliferative activity of mesenchymal stromal cells”, Zhurnal Tekhnicheskoi Fiziki, 90:9 (2020), 1596–1600; Tech. Phys., 65:9 (2020), 1530–1534
Linking options:
https://www.mathnet.ru/eng/jtf5220 https://www.mathnet.ru/eng/jtf/v90/i9/p1596
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Abstract page: | 38 | Full-text PDF : | 24 |
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