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Zhurnal Tekhnicheskoi Fiziki, 2020, Volume 90, Issue 9, Pages 1596–1600
DOI: https://doi.org/10.21883/JTF.2020.09.49696.27-20
(Mi jtf5220)
 

III International Conference Physics -- Life Sciences
Polymer materials for biomedicine

The effect of ammonium chloride on the structure of hydroxyapatite nanoparticles and the proliferative activity of mesenchymal stromal cells

I. P. Dobrovol'skayaab, K. V. Malafeeva, Yu. A. Nashchekinaac, I. A. Kasatkind, E. N. Popovab, V. E. Yudinab

a Peter the Great St. Petersburg Polytechnic University
b Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg
c Institute of Cytology Russian Academy of Science, St. Petersburg
d Saint Petersburg State University
Abstract: Synthetic hydroxyapatite nanoparticles that contain ammonium chloride crystals are obtained. The X-ray diffraction, thermogravimetric analysis, and BET methods show that ammonium chloride crystals are decomposed in argon in the temperature range of $T$ = 220–270$^\circ$C. The heat treatment at $T$ = 300$^\circ$C gives thermal stability to the nanoparticles. The presence of ammonium chloride in the culture medium has a substantial effect on the biocompatibility of nanoparticles. An increase in its content reduces the proliferative activity of mesenchymal stromal cells.
Funding agency Grant number
Russian Science Foundation 19-73-30003
This work was supported by the Russian Science Foundation, project no. 19-73-30003.
Received: 21.01.2020
Revised: 10.04.2020
Accepted: 10.04.2020
English version:
Technical Physics, 2020, Volume 65, Issue 9, Pages 1530–1534
DOI: https://doi.org/10.1134/S106378422009011X
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: I. P. Dobrovol'skaya, K. V. Malafeev, Yu. A. Nashchekina, I. A. Kasatkin, E. N. Popova, V. E. Yudin, “The effect of ammonium chloride on the structure of hydroxyapatite nanoparticles and the proliferative activity of mesenchymal stromal cells”, Zhurnal Tekhnicheskoi Fiziki, 90:9 (2020), 1596–1600; Tech. Phys., 65:9 (2020), 1530–1534
Citation in format AMSBIB
\Bibitem{DobMalNas20}
\by I.~P.~Dobrovol'skaya, K.~V.~Malafeev, Yu.~A.~Nashchekina, I.~A.~Kasatkin, E.~N.~Popova, V.~E.~Yudin
\paper The effect of ammonium chloride on the structure of hydroxyapatite nanoparticles and the proliferative activity of mesenchymal stromal cells
\jour Zhurnal Tekhnicheskoi Fiziki
\yr 2020
\vol 90
\issue 9
\pages 1596--1600
\mathnet{http://mi.mathnet.ru/jtf5220}
\crossref{https://doi.org/10.21883/JTF.2020.09.49696.27-20}
\elib{https://elibrary.ru/item.asp?id=44154283}
\transl
\jour Tech. Phys.
\yr 2020
\vol 65
\issue 9
\pages 1530--1534
\crossref{https://doi.org/10.1134/S106378422009011X}
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