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This article is cited in 1 scientific paper (total in 1 paper)
III International Conference Physics -- Life Sciences
Physical methods in photobiology
Stimulation of $col2a$1 gene expression with low-power laser radiation as a means to induce cartilage formation
M. S. Bozhokinab, D. B. Vcherashniic, S. G. Yastrebovc, L. L. Beylinsonc, M. G. Khotinb a Wreden Research Institute of Traumatology and Orthopedics, St. Petersburg, Russia
b Institute of Cytology Russian Academy of Science, St. Petersburg
c Ioffe Institute, St. Petersburg
Abstract:
Elevated expression of the $col2a$1 gene responsible for synthesis of type II collagen, a major extracellular matrix protein of hyaline cartilage, was observed in multipotent stem cells of rat bone marrow exposed to low-power laser radiation with a wavelength of 0.63 $\mu$m and power of 1.7 mW. The result suggests that this procedure may be employed in treatment of diseases associated with damage to the surface of articular cartilage.
Keywords:
low-intensity laser radiation, chondrogenesis, type II collagen, hyaline cartilage.
Received: 22.01.2020 Revised: 22.01.2020 Accepted: 17.02.2020
Citation:
M. S. Bozhokin, D. B. Vcherashnii, S. G. Yastrebov, L. L. Beylinson, M. G. Khotin, “Stimulation of $col2a$1 gene expression with low-power laser radiation as a means to induce cartilage formation”, Zhurnal Tekhnicheskoi Fiziki, 90:9 (2020), 1586–1588; Tech. Phys., 65:9 (2020), 1521–1523
Linking options:
https://www.mathnet.ru/eng/jtf5218 https://www.mathnet.ru/eng/jtf/v90/i9/p1586
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