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III International Conference Physics -- Life Sciences
Radiospectrometric methods in sciences of life
Optimization of parameters of RF pulse sequences for MRI investigations in the presence of magnetic nanoparticles
Yu. V. Bogacheva, A. V. Nikitinaa, V. V. Frolovb, Ya. Yu. Marchenkoa, B. P. Nikolaeva a Saint Petersburg Electrotechnical University "LETI"
b Saint Petersburg State University
Abstract:
The influence of parameters of various pulsed radio frequency (RF) sequences on the contrast of magnetic resonance (MR) images is investigated. A program for modeling of magnetic resonance imaging (MRI) tomograms and determining the optimal values of pulse RF sequences parameters to achieve the best contrast of MR images has been developed. This program has been tested for MRI studies using negative contrast agents based on magnetic iron oxide nanoparticles and positive contrast agents based on gadolinium. Their influence on MR signal intensity depending on concentration is analyzed. Recommendations on the choice of optimal values of RF sequences parameters for MRI diagnostics using contrasting agents are developed.
Keywords:
MRI, radio frequency pulse sequence, magnetic nanoparticles, theranostic.
Received: 19.12.2019 Revised: 19.12.2019 Accepted: 17.02.2020
Citation:
Yu. V. Bogachev, A. V. Nikitina, V. V. Frolov, Ya. Yu. Marchenko, B. P. Nikolaev, “Optimization of parameters of RF pulse sequences for MRI investigations in the presence of magnetic nanoparticles”, Zhurnal Tekhnicheskoi Fiziki, 90:9 (2020), 1475–1480; Tech. Phys., 65:9 (2020), 1416–1420
Linking options:
https://www.mathnet.ru/eng/jtf5202 https://www.mathnet.ru/eng/jtf/v90/i9/p1475
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Abstract page: | 46 | Full-text PDF : | 30 |
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