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Zhurnal Tekhnicheskoi Fiziki, 2020, Volume 90, Issue 9, Pages 1475–1480
DOI: https://doi.org/10.21883/JTF.2020.09.49678.419-19
(Mi jtf5202)
 

III International Conference Physics -- Life Sciences
Radiospectrometric methods in sciences of life

Optimization of parameters of RF pulse sequences for MRI investigations in the presence of magnetic nanoparticles

Yu. V. Bogacheva, A. V. Nikitinaa, V. V. Frolovb, Ya. Yu. Marchenkoa, B. P. Nikolaeva

a Saint Petersburg Electrotechnical University "LETI"
b Saint Petersburg State University
Abstract: The influence of parameters of various pulsed radio frequency (RF) sequences on the contrast of magnetic resonance (MR) images is investigated. A program for modeling of magnetic resonance imaging (MRI) tomograms and determining the optimal values of pulse RF sequences parameters to achieve the best contrast of MR images has been developed. This program has been tested for MRI studies using negative contrast agents based on magnetic iron oxide nanoparticles and positive contrast agents based on gadolinium. Their influence on MR signal intensity depending on concentration is analyzed. Recommendations on the choice of optimal values of RF sequences parameters for MRI diagnostics using contrasting agents are developed.
Keywords: MRI, radio frequency pulse sequence, magnetic nanoparticles, theranostic.
Funding agency Grant number
Ministry of Education and Science of the Russian Federation 3.6522.2017
This study was supported by the Ministry of Education and Science of the Russian Federation, project no. 3.6522.2017.
Received: 19.12.2019
Revised: 19.12.2019
Accepted: 17.02.2020
English version:
Technical Physics, 2020, Volume 65, Issue 9, Pages 1416–1420
DOI: https://doi.org/10.1134/S106378422009008X
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: Yu. V. Bogachev, A. V. Nikitina, V. V. Frolov, Ya. Yu. Marchenko, B. P. Nikolaev, “Optimization of parameters of RF pulse sequences for MRI investigations in the presence of magnetic nanoparticles”, Zhurnal Tekhnicheskoi Fiziki, 90:9 (2020), 1475–1480; Tech. Phys., 65:9 (2020), 1416–1420
Citation in format AMSBIB
\Bibitem{BogNikFro20}
\by Yu.~V.~Bogachev, A.~V.~Nikitina, V.~V.~Frolov, Ya.~Yu.~Marchenko, B.~P.~Nikolaev
\paper Optimization of parameters of RF pulse sequences for MRI investigations in the presence of magnetic nanoparticles
\jour Zhurnal Tekhnicheskoi Fiziki
\yr 2020
\vol 90
\issue 9
\pages 1475--1480
\mathnet{http://mi.mathnet.ru/jtf5202}
\crossref{https://doi.org/10.21883/JTF.2020.09.49678.419-19}
\elib{https://elibrary.ru/item.asp?id=44154265}
\transl
\jour Tech. Phys.
\yr 2020
\vol 65
\issue 9
\pages 1416--1420
\crossref{https://doi.org/10.1134/S106378422009008X}
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