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This article is cited in 4 scientific papers (total in 4 papers)
ANALYSIS AND MODELING OF COMPLEX LIVING SYSTEMS
The dynamics of polynucleotide chain consisting of two different homogeneous sequences, divided by interface
A. A. Grinevich, A. A. Ryasik, L. V. Yakushevich Institute of cell biophysics, 3 Institutskaya street, Puschino, 142290, Russia
Abstract:
To research dynamics of inhomogeneous polynucleotide DNA chain the Y-model with no dissipation term was used. Basing on this model using numerical methods calculations were carried out, which have shown the behaviour of nonlinear conformational excitation (kink), spreading along the inhomogeneous polynucleotide chain, consisting of two different homogeneous nucleotide sequences. As numerical analysis shows there are three ways of behaviour of the nonlinear kink excitation spreading along the DNA chain. After reaching the interface between two homogeneous sequences consisting of different types of bases kink can a) reflect, b) pass the interface with acceleration (increase its velocity), c) pass the interface with deceleration (decrease its velocity).
Keywords:
ДНК, solitons, DNA, Y-model, sine-Gordon equation, numerical methods.
Received: 05.02.2013
Citation:
A. A. Grinevich, A. A. Ryasik, L. V. Yakushevich, “The dynamics of polynucleotide chain consisting of two different homogeneous sequences, divided by interface”, Computer Research and Modeling, 5:2 (2013), 241–253
Linking options:
https://www.mathnet.ru/eng/crm396 https://www.mathnet.ru/eng/crm/v5/i2/p241
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