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This article is cited in 1 scientific paper (total in 1 paper)
ANALYSIS AND MODELING OF COMPLEX LIVING SYSTEMS
Motion of DNA open states influenced by random force
A. A. Grinevich, A. A. Ryasik, L. V. Yakushevich Institute of Cell Biophysics RAS, 3 Institutskaya st., Pushchino, 142290, Russia
Abstract:
It is known that in the native state the DNA molecule always contains some amount of locally unwound regions, often called the open states of DNA. It is believed that these states play an important role in DNA-protein recognition and that the study of the open states dynamics may shed further light on the mechanisms of regulation of transcription and replication. In this paper we consider the effect of the thermostat on the movement of the open states in the artificial sequence consisting of four homogeneous regions. We construct the energetic profile of the sequence and investigate the trajectories of the movement of the open states under the action of a random force.
Keywords:
DNA open states, solitons, random force.
Received: 09.06.2015 Revised: 15.10.2015
Citation:
A. A. Grinevich, A. A. Ryasik, L. V. Yakushevich, “Motion of DNA open states influenced by random force”, Computer Research and Modeling, 7:6 (2015), 1295–1307
Linking options:
https://www.mathnet.ru/eng/crm294 https://www.mathnet.ru/eng/crm/v7/i6/p1295
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Abstract page: | 142 | Full-text PDF : | 41 | References: | 24 |
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